High Standards Ensure JBC Articles Stay Significant and Enduring

A dedicated medical researcher and educator, Sam W. Lee divides his time between teaching at Harvard and completing studies through the Massachusetts General Hospital Cutaneous Biology Research Center and Broad Institute. Sam W. Lee also serves as a reviewer for more than 15 medical journals, including the Journal of Biological Chemistry (JBC).

In its efforts to provide the scientific community with significant research, the JBC adheres to strict data presentation and high-quality review standards. All manuscripts accepted for the publication are made available to the public for free, and anyone can access these manuscripts through the JBC Papers in Press page.

Because of its high standards and commitment to reaching all types of readers, the JBC ensures that scientists can share their findings with the world efficiently and effectively. The Journal strives to keep review times short and typically takes around 21 days to decide on accepting manuscripts.

Further, the Journal’s review process relies on vetted editorial board members who have demonstrated their experience and knowledge and completed a comprehensive training process. This guarantees that the review process is accurate and uniform across all types of manuscripts.

AAAS Center for Science Diplomacy Promotes International Collaboration

For more than two decades, Sam W. Lee has been studying and teaching a range of medical topics. An associate professor of dermatology at Harvard Medical School and a successful cancer biology researcher, Sam W. Lee belongs to the American Association for the Advancement of Science (AAAS).

Dedicated to advancing innovation and science to benefit people around the world, AAAS maintains several programs and initiatives, including the Center for Science Diplomacy. This international program promotes scientific cooperation by building bridges between countries and including science as an important part of foreign policy.

Established in 2008, the Center for Science Diplomacy focuses on three main levels: operational, inspirational, and intellectual. Through these levels, the Center builds a community of science diplomacy stakeholders and creates a strong foundation for defining and analyzing problems relating to science diplomacy. 

The Center for Science Diplomacy maintains an open-access policy journal and provides various awards through the financial support of the Richard Lounsbery Foundation and Golden Family Foundation.

The CSPSP Addresses AAAS Objectives Relating to Science and Society

Successful medical professional Sam W. Lee, PhD, teaches dermatology as an associate professor at Harvard University and conducts research into cancer biology. Active within the professional community, Dr. Sam W. Lee maintains active membership with several organizations, including the American Association for the Advancement of Science (AAAS).

In an effort to advance science and innovation, the AAAS maintains numerous programs, several of which focus on science, policy, and society. These activities are primarily categorized within the organization’s Center of Science, Policy and Society Programs (CSPSP).

The AAAS maintains four units within its CSPSP: research competitiveness; science and technology policy fellowships; scientific responsibility, human rights, and law; and dialogue on science, ethics, and religion. These units focus on government, society, and the research community and address such AAAS objectives as fostering scientific freedom and promoting human welfare.

In addition to these four units, the CSPSP completes numerous activities through its affiliation with the R&D Budget and Policy Program and Office of Government Relations. It hosts a Visiting Scholar Program that allows professionals to advance their education at the AAAS headquarters, along with an annual Leadership Seminar in Science and Technology Policy.

Overlooked Cities in Asia

A dedicated researcher and academic, Sam W. Lee, PhD, has been working in the medical field for more than two decades. He serves as an associate professor at Harvard Medical School and the deputy director of the MGH/Harvard Cutaneous Biology Research Center. Outside of work, Dr. Sam W. Lee enjoys exploring new cultures and locations throughout Asia.

The largest continent, Asia plays hosts to major cities like Beijing and Seoul that many travelers want to visit. Unfortunately, this leaves numerous cities unexplored by foreigners, despite being just as interesting. Below are some of Asia’s top overlooked cities:

- Busan, South Korea. Located roughly three and a half hours away from Seoul, Busan features amazing local cuisine and unique sights. Packed with attractions to keep visitors busy, it is located along a coastline that includes several beaches.

- Chengdu, China. Backpackers are often familiar with Chengdu due to its being a stopping point on the journey to Tibet. However, the laid-back city has a great deal to offer visitors who stay longer than one night. Voted one of the more livable cities in China, it hosts several parks and tea shops and the entrance to the Jinsha Excavation Site.

- Onomichi, Japan. Offering a relaxed vibe, Onomichi is popular among locals, but largely unknown to foreigners. Over the years, it has drawn attention from anime, manga, film, and numerous other Japanese artists, thanks to its small-town feel and abundance of shrines and temples.

- Kaohsiung, Taiwan. The second-largest city in Taiwan, Kaohsiung has gone from a polluted industrial hub to a fascinating destination. Complete with historical buildings, untouched forests, annual festivals, and numerous waterways, the city is certainly worth seeing.

Research Into Tumor Cells and p53-Mediated Transcriptional Regulation

Dr. Sam W. Lee is a longtime Harvard Medical School dermatology professor who holds responsibilities as associate director with the Massachusetts General Hospital’s Cutaneous Biology Research Center. Dr. Sam W. Lee also serves as a National Institutes of Health (NIH) chartered committee member within the oncology program.

Dr. Lee’s primary research focus is on tumor suppressor p53-mediated transcriptional regulation and how this determines whether cells live or die. Through apoptosis (programmed cell death), radiation, and chemo, agents are able to generate genotoxic stress that eliminates tumor cells. At the same time, the transcription factor p53 is activated when cellular stresses occur. This factor governs a number of essential cellular programs, from apoptosis to cell cycle arrest.

The function of p53 extends to post-apoptotic events and its role in quickly and efficiently clearing apoptotic cells helps maintain tolerance when physiological conditions occur and prevent inflammation. This role as master regulator is accomplished though the new target DD1α and enables a dead cell phagocytic engulfment process following ionizing radiation and other apoptotic stresses.

Korean Society for Molecular Biology - Ilchun Memorial Lecture Award

Sam W. Lee is a Harvard professor and accomplished medical researcher in the fields of oncology, molecular biology, and cutaneous biology. A widely published scientist and sought-after speaker, Sam W. Lee is a Korean Society for Molecular Biology (KSMB) Ilchun Memorial Lecture Award winner. 

KSMB is a professional organization dedicated to promoting scientific collaboration and advancement in the field of molecular biology. Since 1989, it has worked to promote ongoing research and offer educational resources to molecular biologists both in and outside of the Korean community.

KSMB presents several awards to outstanding physicians and researchers at its annual meeting each year. These include the Ilchun Memorial Lecture Award, which is named in honor of professor Ki-Nyung Lee, who was better known by his pen name “Ilchun.” The award is presented to a leading scientist from overseas. Each year's winner is invited to address the KSMB during a special lecture at the annual meeting.

MLS Fans Suggest Footy McFooty Face as Name for San Diego's Team

Aside from his work as the associate director of the Harvard Cutaneous Biology Research Center at Massachusetts General Hospital, Dr. Sam W. Lee also serves as an associate professor of dermatology at Harvard Medical School. Outside of Sam W. Lee’s professional life, he enjoys watching American soccer. 

With Major League Soccer (MLS) set to expand their number of teams in the coming years, fans in San Diego, California, are hopeful that the Southern California city will get in on the action. They are also hopeful that the team will be named, “Footy McFooty Face,” according to an online poll. 

If the name sounds slightly familiar, it might be because the series of events mirrors a similar poll last year, where the Internet voted to name a $300 million British research ship Boaty McBoatface. That poll was rejected by the United Kingdom’s Science Minister, who said the important vessel needed a more “suitable” name. 

Still, Footy McFooty Face leads the poll with over 7,000 votes, while the nearest alternative is the less silly San Diego Surf with less than half that number of votes. FS Investors, the group behind the poll, will submit the top 10 results to the MLS for review, but like Boaty McBoatface, fans probably should not expect San Diego’s soccer team to don a Footy McFootyface kit, whether it leads the polls or not.

The American Association for Cancer Research Annual Meeting

As associate director of the Cutaneous Biology Research Center at Massachusetts General Hospital in Boston, Dr. Sam W. Lee works directly with a multidisciplinary team of investigators dedicated to advancing the understanding of biology. Additionally, Dr. Sam W. Lee is an associate professor of dermatology at Harvard Medical School and a member of several professional organizations, including the American Association for Cancer Research (AACR).

The AACR held its 2016 annual meeting in New Orleans, Louisiana, last April. The theme for the event was “Delivering Cures Through Cancer Science.” 

Sessions emphasized the link between advances in research and improved patient care. At the meeting, numerous discoveries and clinical trials were discussed.

A number of respected speakers took part in the event, including Vice President Joe Biden, who addressed attendees during a plenary session entitled “Highlights 2016: Vision for the Future.” Vice president Biden expressed thanks for the dedicated work of everyone present and encouraged the group to continue the fight for the eradication of cancer.

Opera Etiquette Tips

Sam W. Lee, PhD, brings substantial experience to his roles as the associate director of the Cutaneous Biology Research Center at Massachusetts General Hospital and an associate professor of dermatology at Harvard Medical School. Moreover, Dr. Sam W. Lee is an avid operagoer in his free time. As first-time operagoers may be unfamiliar with opera etiquette, here are some tips.

1. Grant the overture the respect it deserves and listen in silence. Applause is generally reserved for the arias that highlight the performance.

2. Don’t obsess about dress; while many enjoy dressing up, you don’t necessarily have to follow their example. Many will arrive in more casual attire.

3. Remember Italian gender linguistics. When praising a male performance, shout “bravo,” but use “brava” for a female performance. “Bravi” is the acceptable form of praise for a group performance. Alternatively, you could whistle, shout, or remain silent.

4. Although opera running times can vary substantially, they usually fall in the two- to three-hour range. It is advisable to eat beforehand.

Three Must-Visit Historical Sites Around the World

Sam W. Lee teaches at Harvard Medical School as an associate professor. He also serves as the associate director of the nearby Cutaneous Biology Research Center, operated by Massachusetts General Hospital. When he finds time away from work, Sam W. Lee enjoys traveling. He is especially fond of visiting historical sites of note.

Many of the world's oldest and most influential historical sites are open or partially open to tourists. If you enjoy world history, consider visiting one of the following historical sites on your next vacation. 

- Angkor Wat in Cambodia. This 12th-century temple, built by King Suryavaraman II, is a prime example of Khmer-era architecture. The beautiful edifices draw many tourists, so it is best to visit early or late in the day.

- Stonehenge in England. More than 3,000 years old, this well-known monument is full of mysteries. Scholars know that the stones comprising the structure came from Wales, but they do not know how they got to their present location or why they were placed there. A fence prevents visitors from walking inside the circle of stones, but the view is still worth a trip.

- Petra in Jordan. Formerly the capital of the Nabataean Empire for more than 500 years, this 6th-century BC wonder was carved directly into a sandstone cliff. It is now a UNESCO World Heritage Site and very welcoming to tourists.

Seborrheic Keratosis Characteristics

Sam W. Lee attended the University of California to pursue his Ph.D. in genetics. Additionally, he went on to study cancer genetics at Harvard Medical School in Boston, Massachusetts. Currently, Sam W. Lee serves as an associate biologist at Massachusetts General Hospital. One of his focus areas is dermatology.

Dermatology is the branch of medicine that provides diagnosis and treatment for skin conditions such as seborrheic keratosis. A common, benign skin growth, middle-aged adults and older adults may notice these growths more. While it’s common to have multiple growths with seborrheic keratosis, some people may experience just one.

As the growths start to appear, they may develop throughout the body, and appear on the back, abdomen, chest, shoulders, and scalp. Seborrheic keratosis growths start out small with a rough texture. As the growth progresses, it may take on a thick, wart-like appearance. Waxy, raised surfaces are another way to describe these growths. 

If you believe you have this type of growth on your body, it’s important to recognize the texture as it can be hard to distinguish from melanoma growths. It is best to have a doctor evaluate and determine the final diagnosis.

The AAAS - Fighting for Evidence-Based Policies in Congress

Professor Sam W. Lee teaches dermatology at Harvard Medical School and, at the same time, serves as the associate director of the nearby Cutaneous Biology Research Center. Sam W. Lee is also a member of the American Association for the Advancement of Science.

The American Association for the Advancement of Science (AAAS) is a society of scientists and allied professionals who believe that science, engineering, and math have the potential to solve real problems in today's world. It seeks to defend the integrity of science and promote evidence-based policy decisions made by the U.S. Congress. 

The AAAS' Office of Government Relations supports the scientists who work with and advise members of Congress. It is dedicated to providing objective information to our nation's policymakers and to helping them navigate the associated political and cultural challenges.

In recent months, the Office of Government Relations has focused on climate change and the role that scientific evidence plays in the formulation of American policy. Leaders from the AAAS and eight other scientific organizations wrote to Congress in June 2016, reminding lawmakers that the reality of climate change is supported by a vast body of peer-reviewed science.

A Brief Overview of Acne Scarring Prevention

 

A graduate of the University of California, Sam W. Lee has worked as an associate professor of dermatology at Harvard Medical School in Boston since 1999. Dr. Sam W. Lee is also a member of the foundation grant review Committee in the dean’s office.

Acne is a skin condition that can lead to discomfort and physical insecurities. If improperly treated, acne can result in scars that may last far longer than the condition itself.

In some cases, excessive or overly sensitive acne may scar on its own. However, scarring often results from repeated squeezing or picking at infected areas.

To avoid scarring, individuals should refrain from directly touching their acne. Preventing acne is the most effective method of avoiding acne scarring.

Many facial cleansers that keep pores clean and open are on the market, while acne products can provide further topical support. Individuals should also monitor their diets. Unhealthy eating can contribute to the problem of acne.

The Longest-Running Musical in Broadway History

 

An associate professor of dermatology at Harvard Medical School, Sam W. Lee is an avid supporter of the arts. Sam W. Lee is particularly fond of traveling to New York City with his family and attending Broadway shows.

No Broadway musical has matched the longevity of Andrew Lloyd Webber’s The Phantom of the Opera. In 2006, the production overtook Cats as the longest-running show in Broadway history, with 7,486 performances. That show count has since surpassed 12,000.

In London, The Phantom of the Opera ran at Her Majesty’s Theater for more than three decades, logging an additional 12,000 performances. On Broadway, the 1996 revival of Chicago has run for more than 8,000 performances, second to Phantom by nearly 4,000 shows.

Andrew Lloyd Webber’s The Phantom of the Opera has won more than 70 major honors and awards, including a Tony Award for Best Musical, six additional Tony Awards, seven Drama Desk Awards, and three Olivier Awards in the UK.

DF/HCC’s Cancer Care Delivery Research Program

 

Associate Professor Sam W. Lee teaches courses on dermatology at Harvard Medical School in Boston, Massachusetts. Sam W. Lee also serves as a full member of Dana-Farber/Harvard Cancer Center (DF/HCC), which pools together resources of the university’s cancer research community.

At the core of DF/HCC’s work are some of Boston’s medical facilities, namely Beth Israel Deaconess Medical Center, Boston Children’s Hospital, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, and the Massachusetts General Hospital. The Harvard Medical School and the Harvard T.H. Chan School of Public Health also form part of this comprehensive cancer center. Together with over 1,100 researchers, DF/HCC leads innovative cancer research programs.

DF/HCC heads 18 clinical-based or discipline-based research programs. The Cancer Care Delivery Research Program, a discipline-based program, seeks to improve cancer care by creating cost-effective interventions. It also focuses on eliminating socioeconomic disparities which affect the delivery of cancer treatment. With over 50 investigators, the Cancer Care Delivery Research Program works to ensure the implementation of quality cancer care.